Rhesus iPSC Safe Harbor Gene-Editing Platform for Stable Expression of Transgenes in Differentiated Cells of All Germ Layers

Nonhuman primate (NHP) induced pluripotent stem cells (iPSCs) offer the opportunity to investigate the safety, feasibility, and efficacy of proposed iPSC-derived cellular delivery in clinically relevant in vivo models. However, there is need for stable, robust, and safe labeling methods for NHP iPSC...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther
Asıl Yazarlar: Hong, So Gun, Yada, Ravi Chandra, Choi, Kyujoo, Carpentier, Arnaud, Liang, T. Jake, Merling, Randall K., Sweeney, Colin L., Malech, Harry L., Jung, Moonjung, Corat, Marcus A.F., AlJanahi, Aisha A., Lin, Yongshun, Liu, Huimin, Tunc, Ilker, Wang, Xujing, Palisoc, Maryknoll, Pittaluga, Stefania, Boehm, Manfred, Winkler, Thomas, Zou, Jizhong, Dunbar, Cynthia E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2017
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363312/
https://ncbi.nlm.nih.gov/pubmed/28129126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.10.007
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