Efficient differentiation of cardiomyocytes and generation of calcium-sensor reporter lines from nonhuman primate iPSCs

Nonhuman primate (NHP) models are more predictive than rodent models for developing induced pluripotent stem cell (iPSC)-based cell therapy, but robust and reproducible NHP iPSC-cardiomyocyte differentiation protocols are lacking for cardiomyopathies research. We developed a method to differentiate...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Lin, Yongshun, Liu, Huimin, Klein, Michael, Ostrominski, John, Hong, So Gun, Yada, Ravi Chandra, Chen, Guibin, Navarengom, Keron, Schwartzbeck, Robin, San, Hong, Yu, Zu-Xi, Liu, Chengyu, Linask, Kaari, Beers, Jeanette, Qiu, Lugui, Dunbar, Cynthia E., Boehm, Manfred, Zou, Jizhong
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897327/
https://ncbi.nlm.nih.gov/pubmed/29651156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24074-y
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