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A non-threshold region-specific method for detecting rare variants in complex diseases

A region-specific method, NTR (non-threshold rare) variant detection method, was developed—it does not use the threshold for defining rare variants and accounts for directions of effects. NTR also considers linkage disequilibrium within the region and accommodates common and rare variants simultaneo...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Hsieh, Ai-Ru, Chen, Dao-Peng, Chattopadhyay, Amrita Sengupta, Li, Ying-Ju, Chang, Chien-Ching, Fann, Cathy S. J.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708778/
https://ncbi.nlm.nih.gov/pubmed/29190701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188566
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