Identifying rare and common disease associated variants in genomic data using Parkinson’s disease as a model

BACKGROUND: Genome-wide association studies have been successful in identifying common genetic variants for human diseases. However, much of the heritable variation associated with diseases such as Parkinson’s disease remains unknown suggesting that many more risk loci are yet to be identified. Rare...

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Bibliografiske detaljer
Udgivet i:J Biomed Sci
Main Authors: Lin, Ying-Chao, Hsieh, Ai-Ru, Hsiao, Ching-Lin, Wu, Shang-Jung, Wang, Hui-Min, Lian, Ie-Bin, Fann, Cathy SJ
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
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Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428531/
https://ncbi.nlm.nih.gov/pubmed/25175702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-014-0088-9
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