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Maximal Segmental Score Method for Localizing Recessive Disease Variants Based on Sequence Data

BACKGROUND: Due to the affordability of whole-genome sequencing, the genetic association design can now address rare diseases. However, some common statistical association methods only consider homozygosity mapping and need several criteria, such as sliding windows of a given size and statistical si...

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書目詳細資料
發表在:Front Genet
Main Authors: Hsieh, Ai-Ru, Sie, Jia Jyun, Chang, Chien Ching, Ott, Jurg, Lian, Ie-Bin, Fann, Cathy S. J.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325894/
https://ncbi.nlm.nih.gov/pubmed/32655614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00555
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