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Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety
A series of 3-methylidene-1H-indol-2(3H)-ones substituted with a 5- or 6-pentafluorosulfanyl group has been synthesized by a Knoevenagel condensation reaction of SF(5)-substituted oxindoles with a range of aldehydes. The resulting products were characterized by X-ray crystallography studies and were...
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| Publicado no: | Org Biomol Chem |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5708334/ https://ncbi.nlm.nih.gov/pubmed/28984325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob02289a |
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