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Fibroblast growth factor 2 (FGF2) regulates cytoglobin expression and activation of human hepatic stellate cells via JNK signaling

Cytoglobin (CYGB) belongs to the mammalian globin family and is exclusively expressed in hepatic stellate cells (HSCs) in the liver. In addition to its gas-binding ability, CYGB is relevant to hepatic inflammation, fibrosis, and cancer because of its anti-oxidative properties; however, the regulatio...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Sato-Matsubara, Misako, Matsubara, Tsutomu, Daikoku, Atsuko, Okina, Yoshinori, Longato, Lisa, Rombouts, Krista, Adachi, Jun, Tomonaga, Takeshi, Ikeda, Kazuo, Yoshizato, Katsutoshi, Pinzani, Massimo, Kawada, Norifumi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706471/
https://ncbi.nlm.nih.gov/pubmed/28916723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.793794
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