Fibroblast growth factor 2 (FGF2) regulates cytoglobin expression and activation of human hepatic stellate cells via JNK signaling

Cytoglobin (CYGB) belongs to the mammalian globin family and is exclusively expressed in hepatic stellate cells (HSCs) in the liver. In addition to its gas-binding ability, CYGB is relevant to hepatic inflammation, fibrosis, and cancer because of its anti-oxidative properties; however, the regulatio...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sato-Matsubara, Misako, Matsubara, Tsutomu, Daikoku, Atsuko, Okina, Yoshinori, Longato, Lisa, Rombouts, Krista, Adachi, Jun, Tomonaga, Takeshi, Ikeda, Kazuo, Yoshizato, Katsutoshi, Pinzani, Massimo, Kawada, Norifumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706471/
https://ncbi.nlm.nih.gov/pubmed/28916723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.793794
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