Fibroblast growth factor 2 (FGF2) regulates cytoglobin expression and activation of human hepatic stellate cells via JNK signaling

Cytoglobin (CYGB) belongs to the mammalian globin family and is exclusively expressed in hepatic stellate cells (HSCs) in the liver. In addition to its gas-binding ability, CYGB is relevant to hepatic inflammation, fibrosis, and cancer because of its anti-oxidative properties; however, the regulatio...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Sato-Matsubara, Misako, Matsubara, Tsutomu, Daikoku, Atsuko, Okina, Yoshinori, Longato, Lisa, Rombouts, Krista, Adachi, Jun, Tomonaga, Takeshi, Ikeda, Kazuo, Yoshizato, Katsutoshi, Pinzani, Massimo, Kawada, Norifumi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706471/
https://ncbi.nlm.nih.gov/pubmed/28916723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.793794
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