Selective overexpression of cytoglobin in stellate cells attenuates thioacetamide-induced liver fibrosis in mice

Cytoglobin (CYGB), discovered in hepatic stellate cells (HSCs), is known to possess a radical scavenger function, but its pathophysiological roles remain unclear. Here, for the first time, we generated a new transgenic (TG) mouse line in which both Cygb and mCherry reporter gene expression were unde...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Thi Thanh Hai, Nguyen, Thuy, Le Thi Thanh, Shiota, Akira, Kadono, Chiho, Daikoku, Atsuko, Hoang, Dinh Viet, Dat, Ninh Quoc, Sato-Matsubara, Misako, Yoshizato, Katsutoshi, Kawada, Norifumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294752/
https://ncbi.nlm.nih.gov/pubmed/30552362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36215-4
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