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Selective overexpression of cytoglobin in stellate cells attenuates thioacetamide-induced liver fibrosis in mice
Cytoglobin (CYGB), discovered in hepatic stellate cells (HSCs), is known to possess a radical scavenger function, but its pathophysiological roles remain unclear. Here, for the first time, we generated a new transgenic (TG) mouse line in which both Cygb and mCherry reporter gene expression were unde...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294752/ https://ncbi.nlm.nih.gov/pubmed/30552362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36215-4 |
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