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Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism
Oxygen (O(2)) is required for cytochrome P450 (CYP)-dependent drug metabolism. Cytoglobin (CYGB) is a unique globin expressed exclusively in hepatic stellate cells (HSCs). However, its role in O(2)-dependent metabolism in neighboring hepatocytes remains unknown. This study provides evidence that CYG...
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| Vydáno v: | Lab Invest |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6331008/ https://ncbi.nlm.nih.gov/pubmed/25686096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2015.29 |
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