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ΔNp73 regulates the expression of the multidrug-resistance genes ABCB1 and ABCB5 in breast cancer and melanoma cells - a short report

PURPOSE: Multidrug resistance (MDR) is a major cause of treatment failure. In cancer cells, MDR is often caused by an increased efflux of therapeutic drugs mediated by an up-regulation of ATP binding cassette (ABC) transporters. It has previously been shown that oncogenic ΔNp73 plays an important ro...

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Dettagli Bibliografici
Pubblicato in:Cell Oncol (Dordr)
Autori principali: Sakil, Habib A. M., Stantic, Marina, Wolfsberger, Johanna, Brage, Suzanne Egyhazi, Hansson, Johan, Wilhelm, Margareta T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705756/
https://ncbi.nlm.nih.gov/pubmed/28677036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-017-0340-x
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