Quercetin abrogates chemoresistance in melanoma cells by modulating ΔNp73

BACKGROUND: The alkylating agent Dacarbazine (DTIC) has been used in the treatment of melanoma for decades, but when used as a monotherapy for cancer only moderate response rates are achieved. Recently, the clinical use of Temozolomide (TMZ) has become the more commonly used analog of DTIC-related o...

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Autores principales: Thangasamy, Thilakavathy, Sittadjody, Sivanandane, Mitchell, Geoffrey C, Mendoza, Erin E, Radhakrishnan, Vijayababu M, Limesand, Kirsten H, Burd, Randy
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895613/
https://ncbi.nlm.nih.gov/pubmed/20540768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-282
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