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No More Brain Tangles with ΔNp73
In Alzheimer's disease (AD) neurons suffer dysfunction and death associated with aberrant tau phosphorylation and subsequent neurofibrillary tangles. A new study reveals a surprising neuroprotective role for a truncated p73 isoform (ΔNp73). Aged mice with reduced ΔNp73 levels exhibit tau pathol...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2626131/ https://ncbi.nlm.nih.gov/pubmed/19008105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2008.10.004 |
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