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ΔNp73 Enhances Promoter Activity of TGF-β Induced Genes

The p53 homolog p73 is frequently overexpressed in cancers. Especially the transactivation domain truncated isoform ΔNp73 has oncogenic properties and its upregulation is associated with poor patient survival. It has been shown that ΔNp73 has an inhibitory effect on the transactivation capacity of p...

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Détails bibliographiques
Auteurs principaux: Niemantsverdriet, Maarten, Nagle, Peter, Chiu, Roland K., Langendijk, Johannes A., Kampinga, Harm H., Coppes, Robert P.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517593/
https://ncbi.nlm.nih.gov/pubmed/23236396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050815
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