ΔNp73 Enhances Promoter Activity of TGF-β Induced Genes

The p53 homolog p73 is frequently overexpressed in cancers. Especially the transactivation domain truncated isoform ΔNp73 has oncogenic properties and its upregulation is associated with poor patient survival. It has been shown that ΔNp73 has an inhibitory effect on the transactivation capacity of p...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Niemantsverdriet, Maarten, Nagle, Peter, Chiu, Roland K., Langendijk, Johannes A., Kampinga, Harm H., Coppes, Robert P.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517593/
https://ncbi.nlm.nih.gov/pubmed/23236396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050815
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы