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Polypharmacology of conformationally locked methanocarba nucleosides
A single molecular scaffold can be adapted to interact with diverse targets, either separately or simultaneously. Nucleosides and nucleotides in which ribose is substituted with bicyclo[3.1.0]hexane are an example of a versatile drug-like scaffold for increasing selectivity at their classical target...
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| Publicado no: | Drug Discov Today |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5705437/ https://ncbi.nlm.nih.gov/pubmed/28781163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2017.07.013 |
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