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A Small Molecule – DNA Binding Landscape

This brief account traces the development of a “competition dialysis” method used to characterize the structural and sequence selectivity of DNA binding compounds. The method was inspired by a simple “differential dialysis” method pioneered by Don Crothers to explore base-selective intercalator bind...

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Detalles Bibliográficos
Publicado en:Biopolymers
Autor principal: Chaires, Jonathan B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705039/
https://ncbi.nlm.nih.gov/pubmed/25913470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22660
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