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Drug Binding to DNA·RNA Hybrid Structures

DNA·RNA hybrid duplexes are functionally important structures in gene expression that are underutilized as potential drug targets. Several tools are described here for the discovery and characterization of small molecules capable of the selective recognition of DNA·RNA hybrid structures. Competition...

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Autori principali: Wheelhouse, Richard T., Chaires, Jonathan B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008341/
https://ncbi.nlm.nih.gov/pubmed/19997877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-418-0_4
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