Epigenetic regulation of TIMP1 expression by 8-oxoguanine DNA glycosylase-1 binding to DNA:RNA hybrid

8-Oxoguanine DNA glycosylase-1 (OGG1)-initiated base excision repair pathway is primarily responsible for 7, 8-dihydro-8-oxoguanine (8-oxoG) removal from DNA. Recent studies, however, have shown that 8-oxoG in gene regulatory elements may serve as an epigenetic mark, and OGG1 has distinct functions...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Pan, Lang, Wang, Hui, Luo, Jinhua, Zeng, Ji, Pi, Jiao, Liu, Huijun, Liu, Chi, Ba, Xueqing, Qu, Xiangping, Xiang, Yang, Boldogh, Istvan, Qin, Xiaoqun
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894084/
https://ncbi.nlm.nih.gov/pubmed/31652414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900993RR
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