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Specificity landscapes of DNA binding molecules elucidate biological function
Evaluating the specificity spectra of DNA binding molecules is a nontrivial challenge that hinders the ability to decipher gene regulatory networks or engineer molecules that act on genomes. Here we compare the DNA sequence specificities for different classes of proteins and engineered DNA binding m...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2842033/ https://ncbi.nlm.nih.gov/pubmed/20176964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914023107 |
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