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Specificity landscapes of DNA binding molecules elucidate biological function
Evaluating the specificity spectra of DNA binding molecules is a nontrivial challenge that hinders the ability to decipher gene regulatory networks or engineer molecules that act on genomes. Here we compare the DNA sequence specificities for different classes of proteins and engineered DNA binding m...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2842033/ https://ncbi.nlm.nih.gov/pubmed/20176964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914023107 |
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