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Combinatorial bZIP dimers display complex DNA-binding specificity landscapes
How transcription factor dimerization impacts DNA-binding specificity is poorly understood. Guided by protein dimerization properties, we examined DNA binding specificities of 270 human bZIP pairs. DNA interactomes of 80 heterodimers and 22 homodimers revealed that 72% of heterodimer motifs correspo...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5349851/ https://ncbi.nlm.nih.gov/pubmed/28186491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19272 |
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