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Increasing the affinity of selective bZIP-binding peptides through surface residue redesign
The coiled-coil dimer is a prevalent protein interaction motif that is important for many cellular processes. The basic leucine-zipper (bZIP) transcription factors are one family of proteins for which coiled-coil mediated dimerization is essential for function, and misregulation of bZIPs can lead to...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4088978/ https://ncbi.nlm.nih.gov/pubmed/24729132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2477 |
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