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Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs

Liquid–liquid phase separation (LLPS) is thought to contribute to the establishment of many biomolecular condensates, eukaryotic cell structures that concentrate diverse macromolecules but lack a bounding membrane. RNA granules control RNA metabolism and comprise a large class of condensates that ar...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lin, Yuan, Currie, Simon L., Rosen, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704491/
https://ncbi.nlm.nih.gov/pubmed/28924037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.800466
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