Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior

Phase separation of intrinsically disordered proteins (IDPs) commonly underlies the formation of membraneless organelles, which compartmentalize molecules intracellularly in the absence of a lipid membrane. Identifying the protein sequence features responsible for IDP phase separation is critical fo...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Schuster, Benjamin S., Dignon, Gregory L., Tang, Wai Shing, Kelley, Fleurie M., Ranganath, Aishwarya Kanchi, Jahnke, Craig N., Simpkins, Alison G., Regy, Roshan Mammen, Hammer, Daniel A., Good, Matthew C., Mittal, Jeetain
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261017/
https://ncbi.nlm.nih.gov/pubmed/32393642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2000223117
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars