Carregant...

Comparative roles of charge, π, and hydrophobic interactions in sequence-dependent phase separation of intrinsically disordered proteins

Endeavoring toward a transferable, predictive coarse-grained explicit-chain model for biomolecular condensates underlain by liquid–liquid phase separation (LLPS) of proteins, we conducted multiple-chain simulations of the N-terminal intrinsically disordered region (IDR) of DEAD-box helicase Ddx4, as...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Das, Suman, Lin, Yi-Hsuan, Vernon, Robert M., Forman-Kay, Julie D., Chan, Hue Sun
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682375/
https://ncbi.nlm.nih.gov/pubmed/33139563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2008122117
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!