Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation

Membrane encapsulation is frequently used by the cell to sequester biomolecules and compartmentalize their function. Cells also concentrate molecules into phase-separated protein or protein/nucleic acid “membraneless organelles” that regulate a host of biochemical processes. Here, we use solution NM...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Brady, Jacob P., Farber, Patrick J., Sekhar, Ashok, Lin, Yi-Hsuan, Huang, Rui, Bah, Alaji, Nott, Timothy J., Chan, Hue Sun, Baldwin, Andrew J., Forman-Kay, Julie D., Kay, Lewis E.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
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PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625912/
https://ncbi.nlm.nih.gov/pubmed/28894006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706197114
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