The actin-related p41ARC subunit contributes to p21-activated kinase-1 (PAK1)–mediated glucose uptake into skeletal muscle cells

Defects in translocation of the glucose transporter GLUT4 are associated with peripheral insulin resistance, preclinical diabetes, and progression to type 2 diabetes. GLUT4 recruitment to the plasma membrane of skeletal muscle cells requires F-actin remodeling. Insulin signaling in muscle requires p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Tunduguru, Ragadeepthi, Zhang, Jing, Aslamy, Arianne, Salunkhe, Vishal A., Brozinick, Joseph T., Elmendorf, Jeffrey S., Thurmond, Debbie C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2017
Aiheet:
Molecular Bases of Disease
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704484/
https://ncbi.nlm.nih.gov/pubmed/28972183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.801340
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