Doc2b Protects β-Cells Against Inflammatory Damage and Enhances Function

Loss of functional β-cell mass is an early feature of type 1 diabetes. To release insulin, β-cells require soluble N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) complexes, as well as SNARE complex regulatory proteins like double C2 domain–containing protein β (Doc2b). We hypo...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Aslamy, Arianne, Oh, Eunjin, Olson, Erika M., Zhang, Jing, Ahn, Miwon, Moin, Abu Saleh Md, Tunduguru, Ragadeepthi, Salunkhe, Vishal A., Veluthakal, Rajakrishnan, Thurmond, Debbie C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2018
Assuntos:
Islet Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014558/
https://ncbi.nlm.nih.gov/pubmed/29661782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-1352
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