Syntaxin 4 Mediates NF-κB Signaling and Chemokine Ligand Expression via Specific Interaction With IκBβ

Enrichment of human islets with syntaxin 4 (STX4) improves functional β-cell mass through a nuclear factor-κB (NF-κB)–dependent mechanism. However, the detailed mechanisms underlying the protective effect of STX4 are unknown. For determination of the signaling events linking STX4 enrichment and down...

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Vydáno v:Diabetes
Hlavní autoři: Veluthakal, Rajakrishnan, Oh, Eunjin, Ahn, Miwon, Chatterjee Bhowmick, Diti, Thurmond, Debbie C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2021
Témata:
Islet Studies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980198/
https://ncbi.nlm.nih.gov/pubmed/33526588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0868
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