Syntaxin 4 Expression in Pancreatic β-Cells Promotes Islet Function and Protects Functional β-Cell Mass

Syntaxin 4 (Stx4) enrichment in human and mouse islet grafts improves the success of transplants in reversing streptozotocin (STZ)-induced diabetes in mice, although the underlying molecular mechanisms remain elusive. Toward a further understanding of this, human islets and inducible transgenic mice...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Diabetes
Egile Nagusiak: Oh, Eunjin, Ahn, Miwon, Afelik, Solomon, Becker, Thomas C., Roep, Bart O., Thurmond, Debbie C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Diabetes Association 2018
Gaiak:
Islet Studies
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245223/
https://ncbi.nlm.nih.gov/pubmed/30305365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0259
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