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Syntaxin 4 Up-Regulation Increases Efficiency of Insulin Release in Pancreatic Islets From Humans With and Without Type 2 Diabetes Mellitus

CONTEXT: Evidence suggests that dysfunctional β-cell insulin release precedes type 1 and type 2 diabetes (T1D and T2D, respectively) and that enhancing the efficiency of insulin release from pancreatic islet β-cells may delay/prevent these diseases. We took advantage of the rare opportunity to test...

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Detalles Bibliográficos
Autores principales: Oh, Eunjin, Stull, Natalie D., Mirmira, Raghavendra G., Thurmond, Debbie C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010690/
https://ncbi.nlm.nih.gov/pubmed/24552216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-2221
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