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Munc18c Depletion Selectively Impairs the Sustained Phase of Insulin Release
OBJECTIVE: The Sec1/Munc18 protein Munc18c has been implicated in Syntaxin 4–mediated exocytosis events, although its purpose in exocytosis has remained elusive. Given that Syntaxin 4 functions in the second phase of glucose-stimulated insulin secretion (GSIS), we hypothesized that Munc18c would als...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Diabetes Association
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671048/ https://ncbi.nlm.nih.gov/pubmed/19188424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1059 |
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