Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis

How the Sec1/Munc18–syntaxin complex might transition to form the SNARE core complex remains unclear. Toward this, Munc18c tyrosine phosphorylation has been correlated with its dissociation from syntaxin 4. Using 3T3-L1 adipocytes subjected to small interfering ribonucleic acid reduction of Munc18c...

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Autors principals: Jewell, Jenna L., Oh, Eunjin, Ramalingam, Latha, Kalwat, Michael A., Tagliabracci, Vincent S., Tackett, Lixuan, Elmendorf, Jeffrey S., Thurmond, Debbie C.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082181/
https://ncbi.nlm.nih.gov/pubmed/21444687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201007176
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