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Filamentous Actin Regulates Insulin Exocytosis through Direct Interaction with Syntaxin 4

Glucose-induced insulin exocytosis is coupled to associations between F-actin and SNARE proteins, although the nature and function of these interactions remains unknown. Toward this end we show here that both Syntaxin 1A and Syntaxin 4 associated with F-actin in MIN6 cells and that each interaction...

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Detalhes bibliográficos
Main Authors: Jewell, Jenna L., Luo, Wei, Oh, Eunjin, Wang, Zhanxiang, Thurmond, Debbie C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376824/
https://ncbi.nlm.nih.gov/pubmed/18285343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709876200
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