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Signaling of the p21-activated kinase (PAK1) coordinates insulin-stimulated actin remodeling and glucose uptake in skeletal muscle cells
Skeletal muscle accounts for ~80% of postprandial glucose clearance, and skeletal muscle glucose clearance is crucial for maintaining insulin sensitivity and euglycemia. Insulin-stimulated glucose clearance/uptake entails recruitment of glucose transporter 4 (GLUT4) to the plasma membrane (PM) in a...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Biochem Pharmacol |
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Prif Awduron: | , , , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
2014
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418524/ https://ncbi.nlm.nih.gov/pubmed/25199455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.08.033 |
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