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NOVEL ROLES FOR INSULIN RECEPTOR (IR) IN ADIPOCYTES AND SKELETAL MUSCLE CELLS VIA NEW AND UNEXPECTED SUBSTRATES

The insulin signaling pathway regulates whole-body glucose homeostasis by transducing extracellular signals from the insulin receptor (IR) to downstream intracellular targets, thus coordinating a multitude of biological functions. Dysregulation of IR or its signal transduction is associated with ins...

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Bibliographic Details
Main Authors: Ramalingam, Latha, Oh, Eunjin, Thurmond, Debbie C.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556358/
https://ncbi.nlm.nih.gov/pubmed/23052216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1176-1
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