Doc2b Is a Key Effector of Insulin Secretion and Skeletal Muscle Insulin Sensitivity

Exocytosis of intracellular vesicles, such as insulin granules, is carried out by soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) and Sec1/Munc18 (SM) proteins. An additional regulatory protein, Doc2b (double C2 domain), has recently been implicated in exocytosis from c...

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Bibliographische Detailangaben
Hauptverfasser: Ramalingam, Latha, Oh, Eunjin, Yoder, Stephanie M., Brozinick, Joseph T., Kalwat, Michael A., Groffen, Alexander J., Verhage, Matthijs, Thurmond, Debbie C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2012
Schlagworte:
Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447898/
https://ncbi.nlm.nih.gov/pubmed/22698913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1525
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