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Glucose-stimulated Cdc42 Signaling Is Essential for the Second Phase of Insulin Secretion

The small Rho family GTPases Cdc42 and Rac1 have each been shown to function in insulin exocytosis and are presumed to function in actin remodeling and insulin granule mobilization. However, whether either GTPase is required for the mobilization phase of insulin release (second phase) and are linked...

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Detalles Bibliográficos
Main Authors: Wang, Zhanxiang, Oh, Eunjin, Thurmond, Debbie C.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396332/
https://ncbi.nlm.nih.gov/pubmed/17289663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M610553200
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