Conserved roles for murine DUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons

To better understand transcriptional regulation during human oogenesis and pre-implantation development, we defined stage-specific transcription, which revealed the cleavage stage as highly distinctive. Here, we present multiple lines of evidence that a eutherian-specific, multi-copy retrogene, DUX4...

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Publicat a:Nat Genet
Autors principals: Hendrickson, Peter G., Doráis, Jessie A., Grow, Edward J., Whiddon, Jennifer L., Lim, Jong-Won, Wike, Candice L., Weaver, Bradley D., Pflueger, Christian, Emery, Benjamin R., Wilcox, Aaron L., Nix, David A., Peterson, C. Matthew, Tapscott, Stephen J., Carrell, Douglas T., Cairns, Bradley R.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703070/
https://ncbi.nlm.nih.gov/pubmed/28459457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3844
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