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Histone chaperone FACT represses retrotransposon MERVL and MERVL-derived cryptic promoters

Endogenous retroviruses (ERVs) were usually silenced by various histone modifications on histone H3 variants and respective histone chaperones in embryonic stem cells (ESCs). However, it is still unknown whether chaperones of other histones could repress ERVs. Here, we show that H2A/H2B histone chap...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Chen, Fuquan, Zhang, Weiyu, Xie, Dan, Gao, Tingting, Dong, Zhiqiang, Lu, Xinyi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544220/
https://ncbi.nlm.nih.gov/pubmed/32894293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa732
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