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New Concepts in Dopamine D2 Receptor Biased Signaling and Implications for Schizophrenia Therapy
The dopamine (DA) D2 receptor (D2R) is a G protein-coupled receptor (GPCR) that is a common target for antipsychotic drugs (APDs). D2Rs signal through canonical G protein pathways but also through non-canonical beta-arrestin2 (βarr2) dependent pathways, a property referred to as functional selectivi...
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| Publicado no: | Biol Psychiatry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5702557/ https://ncbi.nlm.nih.gov/pubmed/27832841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.10.011 |
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