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Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity
Functional selectivity (or biased agonism) is a property exhibited by some G protein-coupled receptor (GPCR) ligands, which results in the modulation of a subset of a receptor’s signaling capabilities and more precise control over complex biological processes. The dopamine D2 receptor (D(2)R) exhibi...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4627803/ https://ncbi.nlm.nih.gov/pubmed/26516769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141637 |
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