Elucidation of G-protein and β-arrestin functional selectivity at the dopamine D2 receptor

The neuromodulator dopamine signals through the dopamine D2 receptor (D(2)R) to modulate central nervous system functions through diverse signal transduction pathways. D(2)R is a prominent target for drug treatments in disorders where dopamine function is aberrant, such as schizophrenia. D(2)R signa...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Peterson, Sean M., Pack, Thomas F., Wilkins, Angela D., Urs, Nikhil M., Urban, Daniel J., Bass, Caroline E., Lichtarge, Olivier, Caron, Marc G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2015
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460444/
https://ncbi.nlm.nih.gov/pubmed/25964346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502742112
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