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Deletion of GSK3β in D2R-expressing neurons reveals distinct roles for β-arrestin signaling in antipsychotic and lithium action

Several studies in rodent models have shown that glycogen synthase kinase 3 β (GSK3β) plays an important role in the actions of antispychotics and mood stabilizers. Recently it was demonstrated that GSK3β through a β-arrestin2/protein kinase B (PKB or Akt)/protein phosphatase 2A (PP2A) signaling com...

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Detalhes bibliográficos
Main Authors: Urs, Nikhil M., Snyder, Joshua C., Jacobsen, Jacob P. R., Peterson, Sean M., Caron, Marc G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528495/
https://ncbi.nlm.nih.gov/pubmed/23188793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215489109
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