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A Dopamine D1 Receptor-Dependent β-Arrestin Signaling Complex Potentially Regulates Morphine-Induced Psychomotor Activation but not Reward in Mice

Morphine is a widely used analgesic in humans that is associated with multiple untoward effects, such as addiction and physical dependence. In rodent models, morphine also induces locomotor activity. These effects likely involve functionally selective mechanisms. Indeed, G protein-coupled receptor d...

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Hlavní autoři: Urs, Nikhil M, Daigle, Tanya L, Caron, Marc G
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021093/
https://ncbi.nlm.nih.gov/pubmed/20980993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.186
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