A Dopamine D1 Receptor-Dependent β-Arrestin Signaling Complex Potentially Regulates Morphine-Induced Psychomotor Activation but not Reward in Mice

Morphine is a widely used analgesic in humans that is associated with multiple untoward effects, such as addiction and physical dependence. In rodent models, morphine also induces locomotor activity. These effects likely involve functionally selective mechanisms. Indeed, G protein-coupled receptor d...

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Bibliografiska uppgifter
Huvudupphovsmän: Urs, Nikhil M, Daigle, Tanya L, Caron, Marc G
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2011
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021093/
https://ncbi.nlm.nih.gov/pubmed/20980993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.186
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