α-Synuclein Fibril-induced Inclusion Spread in Rats and Mice Correlates with Dopaminergic Neurodegeneration

Proteinaceous inclusions in neurons, composed primarily of α-synuclein, define the pathology in several neurodegenerative disorders. Neurons can internalize α-synuclein fibrils that can seed new inclusions from endogenously expressed α-synuclein. The factors contributing to the spread of pathology a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neurobiol Dis
Egile Nagusiak: Abdelmotilib, Hisham, Maltbie, Tyler, Delic, Vedad, Liu, Zhiyong, Hu, Xianzhen, Fraser, Kyle B., Moehle, Mark S., Stoyka, Lindsay, Anabtawi, Nadia, Krendelchtchikova, Valentina, Volpicelli-Daley, Laura A., West, Andrew
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701756/
https://ncbi.nlm.nih.gov/pubmed/28576704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.05.014
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak