Sensitivity and Specificity of Phospho-Ser129 α-Synuclein Monoclonal Antibodies

α-Synuclein (α-syn) is an abundant presynaptic protein that is the primary constituent of inclusions that define Lewy body diseases (LBDs). In these inclusions, α-syn is phosphorylated at the serine-129 residue. Antibodies directed to this phosphorylation site are used to measure inclusion abundance...

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Veröffentlicht in:J Comp Neurol
Hauptverfasser: Delic, Vedad, Chandra, Sidhanth, Abdelmotilib, Hisham, Maltbie, Tyler, Wang, Shijie, Kem, Danielle, Scott, Hunter J., Underwood, Rachel N., Liu, Zhiyong, Volpicelli-Daley, Laura A., West, Andrew B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031478/
https://ncbi.nlm.nih.gov/pubmed/29888794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.24468
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