Mitochondrial Respiration Is Reduced in Atherosclerosis, Promoting Necrotic Core Formation and Reducing Relative Fibrous Cap Thickness

OBJECTIVE—: Mitochondrial DNA (mtDNA) damage is present in murine and human atherosclerotic plaques. However, whether endogenous levels of mtDNA damage are sufficient to cause mitochondrial dysfunction and whether decreasing mtDNA damage and improving mitochondrial respiration affects plaque burden...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Arterioscler Thromb Vasc Biol
Egile Nagusiak: Yu, Emma P.K., Reinhold, Johannes, Yu, Haixiang, Starks, Lakshi, Uryga, Anna K., Foote, Kirsty, Finigan, Alison, Figg, Nichola, Pung, Yuh-Fen, Logan, Angela, Murphy, Michael P., Bennett, Martin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Lippincott Williams & Wilkins 2017
Gaiak:
Translational Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701734/
https://ncbi.nlm.nih.gov/pubmed/28970293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310042
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