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Phosphoproteomics of cAMP signaling of Bordetella adenylate cyclase toxin in mouse dendritic cells

The adenylate cyclase toxin (CyaA) of the whooping cough agent Bordetella pertussis subverts immune functions of host myeloid cells expressing the α(M)β(2) integrin (CD11b/CD18, CR3 or Mac-1). CyaA delivers into cytosol of cells an extremely catalytically active adenylyl cyclase enzyme, which disrup...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Novák, Jakub, Fabrik, Ivo, Linhartová, Irena, Link, Marek, Černý, Ondřej, Stulík, Jiří, Šebo, Peter
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701129/
https://ncbi.nlm.nih.gov/pubmed/29176673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14501-x
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